La necrólisis epidérmica tóxica y el síndrome de Stevens-Johnson son reacciones graves provocadas por medicamentos, que predominantemente afectan la piel y las membranas mucosas. Se describe la afección de 75 % de superficie corporal total en una mujer de 43 años de edad, a quien se le administró gamma-globulina intravenosa como tratamiento de elección, con resultados satisfactorios.
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Prins C, Kerdel FA, Padilla RS, Hunziker T, Chimenti S, Viard I, et al. Treatment of toxic epidermal necrolysis with high-dose intravenous immunoglobulins: multicenter retrospective analysis of 48 consecutive cases. Arch Dermatol 2003;139(1):26-32.
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