La selección de un medicamento específico perteneciente a una clase farmacológica debe ser bajo los criterios de eficacia, seguridad, costo y conveniencia. Actualmente, los aintiinflamatorios no esteroideos (AINE) constituyen uno de los grupos de medicamentos más consumidos en el mundo, por lo tanto es de gran importancia la revisión de los aspectos de seguridad de estos fármacos. El presente trabajo tiene el objetivo de analizar bajo las evidencias disponibles hasta ahora, la seguridad de los AINE bajo 3 criterios principales: gastrolesividad, cardiotoxicidad y nefrotoxicidad.
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