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Inhibidores del sistema renina-angiotensina-aldosterona. Diferencias farmacológicas
Resumen
La activación del sistema renina-angiotensina-aldosterona es un mecanismo en cascada que genera hipertensión arterial, cuya estructura ha sido identificada y que actualmente puede ser bloqueada a través de rutas enzimáticas o receptores específicos. La gran diversidad de medicamentos disponibles que actúan en este sistema obliga a seleccionar una sola sustancia. Los inhibidores del sistema renina-angiotensina comparten numerosas características farmacológicas y farmacocinéticas pero no todos son iguales. El conocimiento basado en la evidencia científica permite al clínico elegir el fármaco ideal en cada paciente.
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