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El factor de transcripción nuclear kappa en las enfermedades humanas

Ricardo Orlando Escárcega

Resumen


El factor de transcripción nuclear kappa B (NF-κB) fue descrito por primera vez en 1986. Actualmente ha sido ligado a un sinnúmero de enfermedades metabólicas, inflamatorias y diversos tipos de cáncer, y seguirá siendo de interés en diversos procesos de enfermedad inflamatorios, infecciosos y neoplásicos. El descubrimiento de este factor ha logrado ampliar nuestro conocimiento sobre la regulación de la inflamación y las enfermedades crónicas, así como de los fármacos para tratar dichas enfermedades.

 


Palabras clave


Neoplasias; Diabetes; FN-kappa B; Enfermedades autoinmunes del sistema nervioso

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Referencias


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