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Frecuencia de hipertensión arterial, diabetes y dislipidemia en niños con trasplante renal / Frequency of arterial hypertension, diabetes and dyslipidemia in children after kidney transplants
Resumen
Resumen
Introducción: Los pacientes pediátricos con trasplante renal tienen un riesgo incrementado de desarrollar hipertensión arterial, dislipidemia, intolerancia a los hidratos de carbono y diabetes mellitus, factores de riesgo que se asocian con una mayor morbilidad y mortalidad cardiovascular.
Objetivo: Evaluar la frecuencia de hipertensión arterial, dislipidemia y alteración en el metabolismo de los hidratos de carbono en una cohorte de pacientes pediátricos con trasplante renal durante 2006-2016 en el Hospital Pablo Tobon Uribe, en Colombia.
Material y métodos: Estudio descriptivo retrospectivo en el cual se utilizó estadística descriptiva. Adicionalmente se realizó análisis bivariado para comparar pacientes según el desenlace hipertensión arterial, dislipidemia y alteración en el metabolismo de los hidratos de carbono.
Resultados: De un total de 48 trasplantes renales pediátricos en el periodo estudiado, se obtuvo información completa de 43 pacientes al año de seguimiento. Se observó una frecuencia postrasplante de hipertensión arterial del 86%, de dislipidemia del 48%, de intolerancia a los hidratos de carbono del 14% y de diabetes del 2%.
Conclusiones: En la cohorte evaluada se encontró una alta frecuencia de hipertensión arterial y dislipidemia postrasplante renal. Se sugiere el desarrollo de guías de diagnóstico precoz y tratamiento que permitan disminuir el impacto de estas enfermedades asociadas a riesgo cardiovascular en la vida adulta.
Abstract
Background: Pediatric kidney transplant patients have an increased risk of developing arterial hypertension, dyslipidemia, carbohydrate intolerance and diabetes mellitus, risk factors associated with increased cardiovascular morbidity and mortality.
Objective: This study evaluates the frequency of arterial hypertension, dyslipidemia and alteration in carbohydrate metabolism in a cohort of pediatric kidney transplant patients during 2006-2016 at the Pablo Tobon Uribe Hospital, in Colombia.
Material and methods: Retrospective descriptive study in which descriptive statistics were used. Additionally, a bivariate analysis was performed to compare patients according to the outcome of arterial hypertension, dyslipidemia and alteration in carbohydrate metabolism.
Results: From a total of 48 pediatric kidney transplants in the period studied, complete information was obtained from 43 patients at one year of follow-up. There was a post-transplant frequency of hypertension of 86%, dyslipidemia 48%, carbohydrate intolerance 14% and diabetes of 2%
Conclusions: In the evaluated cohort a high frequency of arterial hypertension and dyslipidemia was found after kidney transplantation. The development of early diagnosis and treatment guidelines is suggested to reduce the impact of these diseases associated with cardiovascular risk in adult life.
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Referencias
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DOI: https://doi.org/10.24875/RMIMSS.M20000009
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