Resumen:
La diabetes mellitus es un grave problema de salud pública en todo el mundo. Es una enfermedad metabólica de predominio en la infancia y se caracteriza por la persistencia de una glucemia elevada como consecuencia de un déficit en la secreción o en la acción de la insulina. Es de evolución crónica e impacta en la calidad de vida de los pacientes. Con el fin de describir los predictores de la calidad de vida de los pacientes con diabetes mellitus tipo 1 en los países latinoamericanos se realizó una búsqueda sistematizada en las bases de datos PubMed, Redalyc, SciELO, Scopus y Web of Science con los términos “SF-36”, “WHOQOL” y “diabetes”. Se identificaron 2168 artículos, de los cuales solo cinco fueron incluidos en el análisis cualitativo. Se encontró que la comorbilidad y las complicaciones disminuyen la calidad de vida de los pacientes con diabetes mellitus tipo 1, y que factores como la adecuada adherencia terapéutica, el buen control metabólico y el bienestar psicosocial y emocional impactan positivamente en la calidad de vida de estos pacientes. La comorbilidad y las complicaciones que presentan los pacientes con diabetes mellitus tipo 1 son los principales predictores de mala calidad de vida.
Abstract
Diabetes mellitus is a serious public health problem worldwide. Type 1 diabetes mellitus is a metabolic disease which prevails in childhood; it is characterized by the persistence of high levels of glucose in the blood as a consequence of a deficit in the secretion or in the action of insulin. Type 1 diabetes mellitus has a chronic evolution and impacts the quality of life of patients. In order to describe the predictors of quality of life of patients with type 1 diabetes mellitus in Latin American countries, a systematic search was carried out in PubMed, Redalyc, SciELO, Scopus and Web of Science databases with the terms “SF-36”, “WHOQOL” and “diabetes”. A total of 2168 articles were identified, out of which only five were included in the qualitative analysis. It was found that comorbidities and complications decrease the quality of life of patients with type 1 diabetes mellitus, and factors such as adequate therapeutic adherence, good metabolic control, psychosocial and emotional well-being have a positive impact on the quality of life of these patients. Comorbidities and complications in patients with type 1 diabetes mellitus are the main predictors of poor quality of life.
1. González BM, Galán IR, Dehli CR, Alvarez RL, Naya LD, Torre EM. Epidemiología de la diabetes tipo 1 en Asturias: 2002-2011. Endocrinologia, diabetes y nutricion. 2018.
2. Lecumberri E, Ortega M, Iturregui M, Quesada JA, Vázquez C, Orozco D. Quality of life and treatment satisfaction in actual clinical practice of patients with Type 1 diabetes mellitus (T1DM) and hypoglycemia treated with insulin degludec. Current medical research and opinion. 2017(just-accepted):1-19.
3. Association AD. Diagnosis and classification of diabetes mellitus. Diabetes care. 2010;33(Suppl 1):S62.
4. Della Manna T, Setian N, Savoldelli RD, Guedes DR, Kuperman H, Menezes Filho HC, et al. Diabetes mellitus in childhood: an emerging condition in the 21st century. Revista da Associação Médica Brasileira. 2016;62(6):594-601.
5. Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nature Reviews Endocrinology. 2017.
6. Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes research and clinical practice. 2010;87(1):4-14.
7. Federation ID. DIABETES ATLAS. 8th ed. Bruselas, Bélgica2017.
8. Group W. Study protocol for the World Health Organization project to develop a Quality of Life assessment instrument (WHOQOL). Quality of life Research. 1993;2(2):153-9.
9. Group W. The World Health Organization quality of life assessment (WHOQOL): position paper from the World Health Organization. Social science & medicine. 1995;41(10):1403-9.
10. Santiprabhob J, Kiattisakthavee P, Likitmaskul S, Chaichanwattanakul K, Wekawanich J, Dumrongphol H, et al. Glycemic control, quality of life and self-care behavior among adolescents with type 1 diabetes who attended a diabetes camp. The Southeast Asian journal of tropical medicine and public health. 2012;43(1):172-84.
11. Guo J, Whittemore R, Jeon S, Grey M, Zhou ZG, He GP, et al. Diabetes self-management, depressive symptoms, metabolic control and satisfaction with quality of life over time in Chinese youth with type 1 diabetes. Journal of clinical nursing. 2015;24(9-10):1258-68.
12. Hapunda G, Abubakar A, van de Vijver F, Pouwer F. Living with type 1 diabetes is challenging for Zambian adolescents: qualitative data on stress, coping with stress and quality of care and life. BMC endocrine disorders. 2015;15:20.
13. Kalweit KL, Briers N, Olorunju S. The success of various management techniques used in South African children with type 1 diabetes mellitus. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 2015;105(5):400-4.
14. Prahalad P, Tanenbaum M, Hood K, Maahs DM. Diabetes technology: improving care, improving patient-reported outcomes and preventing complications in young people with Type 1 diabetes. 2018.
15. Shalitin S, Peter Chase H. Diabetes technology and treatments in the paediatric age group. International journal of clinical practice Supplement. 2011(170):76-82.
16. Christie D, Thompson R, Sawtell M, Allen E, Cairns J, Smith F, et al. Structured, intensive education maximising engagement, motivation and long-term change for children and young people with diabetes: a cluster randomised controlled trial with integral process and economic evaluation - the CASCADE study. Health technology assessment (Winchester, England). 2014;18(20):1-202.
17. IDF IDF. IDF DIABETES ATLAS Global Fact sheet 8th ed2017.
18. de la Cruz JPS, Morales DLG, Gonzalez-Castro TB, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez L, et al. Quality of life of Latin-American individuals with type 2 diabetes mellitus: A systematic review. Primary care diabetes. 2019.
19. Gomez-Pimienta E, Gonzalez-Castro TB. Decreased Quality of Life in Individuals with Type 2 Diabetes Mellitus Is Associated with Emotional Distress. 2019;16(15).
20. Juarez-Rojop IE, Fortuny-Falconi CM, Gonzalez-Castro TB, Tovilla-Zarate CA, Villar-Soto M, Sanchez ER, et al. Association between reduced quality of life and depression in patients with type 2 diabetes mellitus: a cohort study in a Mexican population. Neuropsychiatric disease and treatment. 2018;14:2511-8.
21. Hart HE, Redekop WK, Berg M, Bilo HJ, Meyboom-de Jong B. Factors that predicted change in health-related quality of life were identified in a cohort of diabetes mellitus type 1 patients. Journal of clinical epidemiology. 2005;58(11):1158-64.
22. Marshall SL, Edidin D, Sharma V, Ogle G, Arena VC, Orchard T. Current clinical status, glucose control, and complication rates of children and youth with type 1 diabetes in Rwanda. Pediatric diabetes. 2013;14(3):217-26.
23. Quah JHM, Wang P, Ng RRG, Luo N, Tan NC. Health‐related quality of life of older Asian patients with multimorbidity in primary care in a developed nation. Geriatrics & gerontology international. 2017;17(10):1429-37.
24. dos Santos KdFR, da Silva PR, Ferreira VT, Domingues EAR, Simões IRA, Lima RS, et al. Quality of life of people with chronic ulcers. Journal of Vascular Nursing. 2016;34(4):131-6.
25. Nemcova J, Hlinkova E, Farsky I, Ziakova K, Jarosova D, Zelenikova R, et al. Quality of Life of Patients with Diabetic Foot Ulcer in the Visegrad Countries. J Clin Nurs. 2016.
26. Rechenberg K, Whittemore R, Grey M. Anxiety in Youth With Type 1 Diabetes. Journal of pediatric nursing. 2017;32:64-71.
27. Vanstone M, Rewegan A, Brundisini F, Dejean D, Giacomini M. Patient Perspectives on Quality of Life With Uncontrolled Type 1 Diabetes Mellitus: A Systematic Review and Qualitative Meta-synthesis. Ont Health Technol Assess Ser. 2015;15(17):1-29.
28. Smith-Palmer J, Bae JP, Boye KS, Norrbacka K, Hunt B, Valentine WJ. Evaluating health-related quality of life in type 1 diabetes: a systematic literature review of utilities for adults with type 1 diabetes. Clinicoecon Outcomes Res. 2016;8:559-71.
29. Glasgow RE, Ruggiero L, Eakin EG, Dryfoos J, Chobanian L. Quality of life and associated characteristics in a large national sample of adults with diabetes. Diabetes care. 1997;20(4):562-7.
30. Gu B, Miao H, Zhang J, Hu J, Zhou W, Gu W, et al. Clinical benefits of autologous haematopoietic stem cell transplantation in type 1 diabetes patients. Diabetes & metabolism. 2017.
31. Snarski E, Szmurło D, Hałaburda K, Król M, Urbanowska E, Milczarczyk A, et al. An economic analysis of autologous hematopoietic stem cell transplantation (AHSCT) in the treatment of new onset type 1 diabetes. Acta diabetologica. 2015;52(5):881-8.
32. Penaforte-Saboia JG, Montenegro Jr RM, Couri CE, Batista LA, Montenegro APD, Fernandes VO, et al. Microvascular Complications in Type 1 Diabetes: A Comparative Analysis of Patients Treated with Autologous Nonmyeloablative Hematopoietic Stem-Cell Transplantation and Conventional Medical Therapy. Frontiers in endocrinology. 2017;8.
33. Shehadeh N, Maor Y. Effect of a new insulin treatment regimen on glycaemic control and quality of life of Muslim patients with type 2 diabetes mellitus during Ramadan fast - an open label, controlled, multicentre, cluster randomised study. International journal of clinical practice. 2015;69(11):1281-8.
34. Gao L, Ji L, Su Q, Feng B, Shan Z, Hu R, et al. Impact of structured self-monitoring of blood glucose on the quality of life of insulin-treated Chinese patients with type 2 diabetes mellitus: Results from the COMPASS study. Diabetes research and clinical practice. 2016;112:88-93.
35. Ridderstrale M, Evans LM, Jensen HH, Bogelund M, Jensen MM, Ericsson A, et al. Estimating the impact of changes in HbA1c, body weight and insulin injection regimen on health related quality-of-life: a time trade off study. Health and quality of life outcomes. 2016;14:13.
36. Hermanns N, Kulzer B, Kohlmann T, Jacob S, Landgraf W, Theobald K, et al. Treatment satisfaction and quality-of-life between type 2 diabetes patients initiating long- vs. intermediate-acting basal insulin therapy in combination with oral hypoglycemic agents – a randomized, prospective, crossover, open clinical trial. Health and Quality of Life Outcomes. 2015;13:77.
37. Novato TdS, Grossi SAA, Kimura M. Quality of life and self-esteem of adolescents with diabetes mellitus. Acta Paulista de enfermagem. 2008;21(4):562-7.
38. Miranzi SdSC, Ferreira FS, Iwamoto HH, Pereira GdA, Miranzi MAS. Qualidade de vida de indivíduos com diabetes mellitus e hipertensão acompanhados por uma equipe de saúde da família. Texto and Contexto Enfermagem. 2008;17(4):672.
39. Santos MAd, Silva AFS, Oliveira-Cardoso ÉAd, Mastropietro AP, Voltarelli JC. Impact of autologous hematopoietic stem cell transplantation on the quality of life of type 1 diabetes mellitus patients. Psicologia: Reflexão e Crítica. 2011;24(2):264-71.
40. Almeida SAd, Silveira MM, Espírito Santo PF PR, Salomé G. Avaliação da qualidade de vida em pacientes com diabetes mellitus e pé ulcerado. Rev Bras Cir Plast. 2013;28(1):142-6.
41. de Ornelas Maia ACC, de Azevedo Braga A, Paes F, Machado S, Carta MG, Nardi AE, et al. Comorbidity of depression and anxiety: association with poor quality of life in type 1 and 2 diabetic patients. Clinical practice and epidemiology in mental health: CP & EMH. 2013;9:136.