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Factores asociados a carga sintomática residual en pacientes con diálisis peritoneal: estudio de cohorte / Factors associated with residual symptom burden in patients with peritoneal dialysis: a cohort study

Ismael Antonio Quintal-Medina, Héctor Isaac Rocha-González, Maura Estela Noyola-García, Miguel Guillermo Flores-Padilla

Resumen


Resumen

Introducción: Los pacientes en diálisis peritoneal presentan síntomas residuales que reducen su calidad de vida.

Objetivo: Determinar los factores asociados a la carga sintomática residual en pacientes con diálisis peritoneal continua ambulatoria (DPCA).

Material y métodos: Estudio observacional, longitudinal, prospectivo y analítico. Se incluyeron pacientes con enfermedad renal crónica candidatos a diálisis peritoneal. Se les aplicó el cuestionario Palliative Care Outcome Scale-Symptoms Renal (POS-S Renal) en prediálisis y a los 3 meses de DPCA. Se determinó la carga sintomática residual a los 3 meses de DPCA con un valor ≥ 8 puntos del cuestionario POS-S Renal. Las variables clínicas y bioquímicas codificadas de forma dicotómica fueron comparadas con la carga sintomática residual. Se calcularon el riesgo relativo (RR), los intervalos de confianza del 95% y los modelos de regresión logística.

Resultados: Se incluyeron 70 pacientes. La media de la tasa de filtrado glomerular fue de 4.7 ± 2 ml/min/1.73 m2. La mediana de la puntuación POS-S Renal en prediálisis fue de 30 puntos y a los 3 meses de la DPCA fue de 8 puntos. La carga sintomática leve prediálisis presentó un RR de 0.18.

Conclusiones: La carga sintomática leve prediálisis es un factor protector independiente de la carga sintomática residual a los 3 meses de la DPCA.

 

Abstract

Background: Patients on peritoneal dialysis have residual symptoms that reduce their quality of life.

Objective: To determine the associated factors of residual symptom burden in patients with continuous ambulatory peritoneal dialysis (CAPD).

Material and mehotds: An observational, longitudinal, prospective and analytical study was carried out in patients with chronic kidney disease, who were candidates for peritoneal dialysis. The Palliative Care Outcome Scale-Symptoms Renal (POS-S Renal) questionnaire was applied in predialysis and 3 months after CAPD. The residual symptom burden was determined three months after CAPD with a value ≥ 8 points of the POS-S Renal questionnaire. The clinical and biochemical variables coded in a dichotomous manner were compared with the residual symptom burden. Relative risk (RR) with 95% confidence intervals and logistic regression models were calculated.

Results: Seventy patients were included. The mean of glomerular filtration rate (GFR) was 4.7 ± 2 ml/min/1.73 m2. The median of the POS-S Renal score in predialysis was 30 points, and 3 months after CAPD was 8 points. The slight symptom burden predialysis presented a RR of 0.18.  

Conclusions: The slight symptom burden predialysis is a protective factor independent for residual symptom burden three months after CAPD. 


Palabras clave


Factores Protectores; Evaluación de Síntomas; Diálisis Peritoneal / Protective Factors; Symptom Assessment; Peritoneal Dialysis

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Referencias


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DOI: https://doi.org/10.24875/RMIMSS.M20000015

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