Resumen
Introducción: el sangrado gastrointestinal de origen oscuro es una entidad poco frecuente y se reserva a los casos en los que ya se ha realizado exploración del intestino delgado (endoscópica/radiológica) sin encontrar la causa. Actualmente el estándar de oro es la videocápsula, que se ha descrito como una técnica segura, útil y eficaz para el diagnóstico y tratamiento de las enfermedades del intestino delgado.
Objetivo: describir variables demográficas, indicaciones, hallazgos, segmento explorado, tratamiento y tiempo de procedimiento quirúrgico de la enteroscopía transoperatoria en 15 pacientes con diagnóstico de sangrado de tubo digestivo de origen oscuro.
Material y métodos: se incluyeron 15 pacientes adultos con el diagnóstico de sangrado de origen oscuro con panendoscopía y colonoscopía negativa a sangrado. A todos se les realizó laparotomía exploradora y enteroscopía transoperatoria con un gastroduodenoscopio.
Resultados: se realizaron 15 enteroscopías transoperatorias con gastroduodenoscopio; 10 en mujeres y 5 en hombres, con promedio de edad de 67.2 años. Se exploró la tercera y cuarta porción del duodeno, yeyuno e íleon terminal. Los diagnósticos encontrados fueron enfermedad de Crohn en 1 paciente (6.66%), adenomas en 2 (13.3%), divertículo yeyunal en 6 (40%) y angiectasias en 6 casos (40%). La localización fue en yeyuno [12 casos (80%)] e íleon [3 casos (20%)].
Conclusiones: la enteroscopía intraoperatoria es una alternativa diagnóstica en el sangrado de origen oscuro cuando no se cuente con la enteroscopía doble balón o la videocápsula endoscópica.
Abstract
Background: Bleeding of dark origin is a rare entity and it is reserved for cases in which exploration of the small intestine has already been performed (endoscopic / radiological) without finding the cause. Currently, the gold standard is the videocapsule which has been described as a safe, useful and effective technique for the diagnosis and treatment of diseases of the small intestine.
Objective: The objective was to describe demographic variables, indications, findings, explored segment, treatment and time of the surgical procedure of the intraoperative enteroscopy in 15 patients with a diagnosis of gastrointestinal bleeding of dark origin.
Material and methods: 15 adult patients with the diagnosis of bleeding of dark origin with panendoscopy and negative colonoscopy to bleeding were included. All of these underwent exploratory laparotomy and intraoperative enteroscopy with a gastroduodenoscope.
Results: 15 intraoperative enteroscopies were performed with a gastroduodenoscope; 10 women and 5 men with an average age of 67.2 years. Third and fourth portions of the duodenum, jejunum, and terminal ileum were explored. The diagnoses found were Crohn’s disease 1 (6.66%), Adenomas 2 (13.3%), jejunal diverticulum 6 (40%) and angiectasias in 6 cases (40%). The location was in jejunum, 12 cases (80%) and ileum, 3 cases (20%).
Conclusions: Intraoperative enteroscopy is a diagnostic alternative in bleeding of dark origin when there is no double balloon enteroscopy or endoscopic video capsule.
Pasha SF, Leighton JA, Das A, et al. Double-balloon enteroscopy and capsule endoscopy have comparable diagnostic yield in small-bowel disease: a meta-analysis. Clin Gastroenterol Hepatol 2008; 6:671.Doi: 10.1016/j.cgh.2008.01.005.
Gerson LB, Fidler JL, Cave DR, et al. ACG Clinical Guideline: Diagnosis and Management of Small Bowel Bleeding. Am J Gastroenterol 2015; 110:1265. DOI: 10.1038/ajg.2015.246
Pennazio M, Spada C, Eliakim R, et al. Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline. Endoscopy 2015; 47:352. DOI: 10.1055/s-0034-1391855
Yamamoto H, Ogata H, Matsumoto T, et al. Clinical Practice Guideline for Enteroscopy. Dig Endosc 2017; 29:519. DOI: 10.1111/den.12883
Szold A, Katz LB, Lewis BS. Surgical approach to occult gastrointestinal bleeding. Am J Surg 1992; 163:90. DOI: 10.1016/0002-9610(92)90258-s
Tee HP, Kaffes AJ. Non-small-bowel lesions encountered during double-balloon enteroscopy performed for obscure gastrointestinal bleeding. World J Gastroenterol 2010; 16:1885. DOI: 10.3748/wjg.v16.i15.1885
Pennazio M, Arrigoni A, Risio M, et al. Clinical evaluation of push-type enteroscopy. Endoscopy 1995; 27:164. DOI: 10.1055/s-2007-1005656
Chong J, Tagle M, Barkin JS, Reiner DK. Small bowel push-type fiberoptic enteroscopy for patients with occult gastrointestinal bleeding or suspected small bowel pathology. Am J Gastroenterol 1994; 89:2143.
Davies GR, Benson MJ, Gertner DJ, et al. Diagnostic and therapeutic push type enteroscopy in clinical use. Gut 1995; 37:346.
Raju GS, Gerson L, Das A, et al. American Gastroenterological Association (AGA) Institute medical position statement on obscure gastrointestinal bleeding. Gastroenterology 2007; 133:1694. DOI: 10.1053/j.gastro.2007.06.008
Zaman A, Sheppard B, Katon RM. Total peroral intraoperative enteroscopy for obscure GI bleeding using a dedicated push enteroscope: diagnostic yield and patient outcome. Gastrointest Endosc 1999; 50:506.
Ress AM, Benacci JC, Sarr MG. Efficacy of intraoperative enteroscopy in diagnosis and prevention of recurrent, occult gastrointestinal bleeding. Am J Surg 1992; 163:94.
Hartmann D, Schmidt H, Bolz G, et al. A prospective two-center study comparing wireless capsule endoscopy with intraoperative enteroscopy in patients with obscure GI bleeding. Gastrointest Endosc 2005; 61:826.DOI: 10.1016/s0016-5107(05)00372-x
Green J, Schlieve CR, Friedrich AK, et al. Approach to the Diagnostic Workup and Management of Small Bowel Lesions at a Tertiary Care Center. J Gastrointest Surg 2018; 22:1034.DOI: 10.1007/s11605-018-3668-2
Gómez RBJ, Romero CR, Hergueta DP, et al . Rendimiento de la enteroscopia. Rev Med Hosp Gen Mex. 2002; 65: 201-206.
Kopácová M, Bures J, Vykouril L, et al. Intraoperative enteroscopy: ten years’ experience at a single tertiary center. Surg Endosc. 2007; 21: 1111-1116. https://doi.org/10.1007/s00464-006-9052-4
Gostout CJ. Sonde enterosopy. Technique, depth of insertion, and yield of lesions. Gastrointest Endoscc Clin North Am. 1996;6:777-92.
Keizman D, Brill S, Umanski M, Rattan Y, Hallak A, Halpern Z, et al. Diagnostic yield of routine push enteroscopy with graded-stiffness enteroscope without overtu-be. Gastrointest Endosc. 2000;57:877-81.
Hayat M, Axon T, O’Mahony. Diagnostic yield and effect on clinical outcomes of push enteroscopy in suspected small-bowell bleeding. Endoscopy. 2003;32:369-72.
Kendrick ML, Buttar NS, Anderson MA, Lutzke LS, Peia D, Wang KK, et al. Con- tribution of intraoperative enteroscopy in the management of obscure gastrointestinal bleeding. J Gastrointest Surg. 2001;5:162-7.
Ress AM, Benacci JC, Sarr MG. Efficacy of intraoperative enteroscopy in diagnosis and prevention of recurrent, occult gastrointestinal bleeding. Am J Surg. 1992;163:94-8.
Taylor AC, Chen RY, Desmond PV. Use of an overtube for enteroscopy:does it in- crease depth of insertion? A prospective study of enteroscopy with and without an overtube. Endoscopy. 2001;33:227-30.
LandiB,TkoubM,GaudricM,GuimbaudR,CervoniJP,ChaussadeS,etal.Diagnostic yield of push type enteroscopy in relation to indication. Gut. 1998;42:421-5.
Chak A, Cooper GS, Canto MI, et al. Enteroscopy for the initial evaluation of iron deficiency. Gastrointest Endosc 1998; 47:144.
Monsanto P, Almeida N, Lérias C, Figuereido P, Gouveia H, Sofia C. Is there a role for intraoperative enteroscopy in patients with obscure gastrointestinal bleeding?Rev Esp Enferm Dig. 2012; 104: 190-196.
Vlachogiannakos J, Papaxoinis K, Viazis N, et al. Bleeding lesions within reach of conventional endoscopy in capsule endoscopy examinations for obscure gastrointestinal bleeding: is repeating endoscopy economically feasible? Dig Dis Sci 2011; 56:1763. DOI: 10.1007/s10620-011-1592-3
Laine L, Sahota A, Shah A. Does capsule endoscopy improve outcomes in obscure gastrointestinal bleeding? Randomized trial versus dedicated small bowel radiography. Gastroenterology 2010; 138:1673. DOI: 10.1053/j.gastro.2010.01.047
Goenka MK, Majumder S, Kumar S, et al. Single center experience of capsule endoscopy in patients with obscure gastrointestinal bleeding. World J Gastroenterol 2011; 17:774. Doi: 10.3748/wjg.v17.i6.774
Jackson CS, Gerson LB. Management of gastrointestinal angiodysplastic lesions (GIADs): a systematic review and meta-analysis. Am J Gastroenterol 2014; 109:474. DOI: 10.1038/ajg.2014.19