Intrarectal povidone-iodine to reduce the risk of genitourinary infections after transrectal prostate biopsy

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Jorge Moreno-Palacios
Alejandro Espinosa-Guerrero
Juan Ramón Torres-Anguiano
Guillermo Montoya-Martínez
Virgilio Augusto López-Sámano
Eduardo Serrano-Brambila

Keywords

Biopsy, Prostate, Urinary tract, Povidone-Iodine

Abstract

Background: The aim of this study is to compare two different preparations in patients undergoing transrectal prostate biopsies samples (TPBS) and assess the prevalence of genitourinary infections (GUI).

Methods: A historical cohort of patients undergoing TBPS for suspected prostate cancer. Two groups were compared: one with endorectal lubricant jelly and another with the addition of a povidone-iodine lubricating jelly. Complications were evaluated at three weeks. A bivariate analysis was performed by calculating the OR (95 % CI) to determine if the additional endorectal povidone-iodine pre-TBPS reduced GUI and other complications. 

Results: 185 patients (Group I n = 86, Group II n = 96) were evaluated. 45 and 25 % had genitourinary tract infection (OR: 0.4, CI: 0.2-0.9, p = 0.004); fever was presented in 21 and 10 % respectively (OR: 0.42, CI: 0.1-0.9, p = 0.04).

Conclusions: A reduction was observed in the presence of genitourinary infections in patients who had intrarectal povidone-iodine preparation applied.

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