Osteosynthesis with 2-octylcyanoacrylate and sodium bicarbonate in zygomatic arch fractures: animal model results

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Mariana García-Tamayo
José Guadalupe González-Martínez
Marco Antonio García-Huerta
Mario Campos-Jiménez
María Luisa Márquez-Rocha

Keywords

Fracture, Tissue adhesive, Biocompatibility, Consolidation

Abstract

Background: the 2 octilcianoacrilate (2OCA) is a liquid monomer that polymerizes on contact with the surface by an exothermic reaction creating a strong and flexible film. Multiple studies have recently demonstrated that wound closure with 2OCA is compared with other methods of closure, offering additional benefits such as tensile strength and compression-resistant joints, highly polymerized fast, also acts as a barrier to microorganisms.  The aim was to use the combination of 2OCA and sodium bicarbonate in the treatment of zygomatic arch fractures in an animal model and to evaluate the biocompatibility and bone healing.

Methods: twenty animals subjected to bilateral zygomatic arch fracture under surgical sedation, and using 2OCA fixation and sodium bicarbonate experimental side and control side floating, watching over a period from two to four weeks, assessing biocompatibility stability and consolidation.

Results: at the end of two and four weeks, the twenty animals showed the presence of osseous callous and continuity of marrow channel measured by macroscopic and radiography examinations.

Conclusions: the use of 2-Octilcianoacrilate and sodium bicarbonate led the stabilization and reduction of bilateral zygomatic arch fractures in an animal model without adverse reactions.

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