Saturation index and fraction of inspired oxygen as a predictor in COVID-19

Authors

  • Shareni Berenice Castro-Arellano <p>Instituto Mexicano del Seguro Social, Hospital General Regional No. 2 &ldquo;Dr. Guillermo Fajardo Ortiz&rdquo;, Servicio de Urgencias. Ciudad de M&eacute;xico, M&eacute;xico .</p> http://orcid.org/0000-0001-9594-4255
  • Laura Elizabeth Sandoval-Mosqueda <p>Instituto Mexicano del Seguro Social, Hospital General de Zona No. 48 &ldquo;San Pedro Xalpa&rdquo;, Servicio de Urgencias. Ciudad de M&eacute;xico, M&eacute;xico.</p> http://orcid.org/0000-0002-3181-7887
  • Francisco Javier Flores-Murrieta <p>Instituto Politecnico Nacional, Secci&oacute;n de Estudios de Posgrado. Ciudad de M&eacute;xico, M&eacute;xico.</p><p>Instituto Nacional de Enfermedades Respiratorias Ismael Cos&iacute;o Villegas, Unidad de Investigaci&oacute;n en Farmacolog&iacute;a. Ciudad de M&eacute;xico, M&eacute;xico.</p> http://orcid.org/0000-0001-9971-5441

DOI:

https://doi.org/10.5281/zenodo.8319752

Keywords:

Oxygen, Hypoxia, Mortality, COVID-19

Abstract

Background: Coronavirus disease leads to silent hypoxia, ARDS, and organ failure. The saturation and fraction of inspired oxygen have been related to the degree of lung damage, can be considered as a monitoring tool for lung function during hospitalization and a predictor of mortality in patients with pneumonia by COVID-19.

Objective: To evaluate the usefulness of the oxygen saturation index and fraction of inspired oxygen as a predictor of mortality in patients with COVID-19 pneumonia.

Material and methods: A retrospective, longitudinal, analytical study. Files of eligible patients with a diagnosis of SARSCoV-2 pneumonia were admitted to HGR No.2, complete file, recording of oxygen saturation and inspired fraction of oxygen, were included. Patients dependent on supplemental oxygen, who did not require supplemental oxygen during their hospitalization, incomplete records, patients who have died from non-pulmonary causes, were excluded.

Results: A sample of 175 records of patients diagnosed with SARS-CoV-2 pneumonia was obtained. A logistic regression model was performed including: age over 60 years, mellitus diabetes, systemic arterial hypertension, SAFI index, and endotracheal intubation.

Conclusion: The SpO2/Fio2 index can be used for continuous monitoring of lung function in patients with COVID-19 pneumonia, in an accessible, easy and economical way. A relationship with mortality was obtained in patients with SpO2/FiO2 less than 310 associated with other factors.

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Published

2023-09-18

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Original Articles