Image features in correlation with biopsy in diabetic mastopathy associated with diabetes type 2
Keywords:
Breast Diseases, Diabetes Mellitus, Ultrasonography, Mammary, BiopsyAbstract
Background: Diabetic mastopathy is an uncommon complication of diabetes mellitus (DM) of long-term evolution which can be confused with breast cancer. Therefore, it is important to know this entity.
Clinical case: The aim of the present study is to show the characteristics of mastography and breast ultrasound (US) in a 54-year-old Mexican woman with DM of 27 years of evolution treated with insulin. This patient presented increased volume in both breasts secondary to diabetic mastopathy. We describe the utility of the US-guided core-needle biopsy as well.
Conclusion: Diabetic mastopathy is a rare morphological change, which requires clinical correlation and proposes the differential diagnosis in physical examination and imaging studies of breast cancer. Breast US is the most useful diagnostic tool to evaluate a palpable nodule in a patient with suspected diabetic mastopathy and the biopsy is the gold standard test which allows the diagnosis.
Downloads
References
Soler NG, Khardori R. Fibrous disease of the breast, thyroiditis, and cheiroarthropathy in type I diabetes mellitus. Lancet. 1984;28:193-5.
Byrd BF Jr, Hartmann WH, Graham LS, Hogle HH. Mastopathy in insulin dependent diabetics. Ann Surg. 1987;205:529-32.
Lakshmanan R, Clarke M J, Putti T C. Diabetic fibrous mastopathy. Singapore Med J. 2007;48:579-81.
American College of Radiology. ACR Breast Imaging Reporting and Data System (BI-RADS) breast imaging atlas. Reston, VA: American College of Radiology; 2013.
Hernández AM, Gutiérrez JP, Reynoso NN. Diabetes mellitus en México. El estado de la epidemia. Salud Pub Méx. 2013;55:5129-36.
Ricart-Selma V, Camps-Herrero J, Martínez-Rubio C, Cano-Muñoz R, González-Noguera PJ, Forment-Navarro M et al. Mastopatía diabética: clínica, hallazgos radiológicos y anatomopatológicos y tratamiento. Radiología. 2011;53:349-54.
D’Alfonso TM, Ginter PS, Shin SJ. A review of inflammatory processes of the breast with a focus on diagnosis in core biopsy samples. J Pathol Trans Med. 2015;49:279-87.
Tomaszewski JE, Brooks JS, Hicks D, Livolsi VA. Diabetic mastopathy: a distinctive clinicopathologic entity. Hum Pathol. 1992;23:780-6.
Kim J, Kim EKK, Moon HJ, Yoon JH. Diabetic mastopathy: imaging features and the role of image-guided biopsy in its diagnosis. Ultrasonography. 2016;35:140-7.
Gokhale S. Ultrasound characterization of breast masses. Indian J Radiol Imaging. 2009;19:242-7.
Crystal P, Koretz M, Shcharynsky S, Makarov V, Strano S. Accuracy of sonographically guided 14-gauge core-needle biopsy: results of 715 consecutive breast biopsies with ar least two-year follow-up of benign lesions. J Clin Ultrasound. 2005;33:47-52.
Moschetta M, Telegrafo M, Triggiani V, Rella L, Cornacchia I, Serio G, et al. Diabetic mastopathy: a diagnostic challenge in breast sonography. J Clin Ultra. 2015;43:113-7.
Kirby RX, Mitchell DI, Williams NP, Cornwall DA, Cawich SO. Diabetic mastopathy: an uncommon complication of diabetes mellitus. Case Rep Surg. 2013;2013:1-4.
Leroux-Stewart J, Rabasa-Lhoret R. Diabetic Mastopathy: case report and summary of literature. Can J Diabetes. 2014;38:305-6.
Valdez R, Thorson J, Finn WG, Schnitzer B, Kleer CG. Lymphocytic mastitis and diabetic mastopathy: a molecular, immunophenotypic, and clinicopathologic evaluation of 11 cases. Mod Pathol. 2003;16:223-8.
Downloads
Published
Issue
Section
License
Authors retain their copyright and grant the Revista Médica del IMSS the right of first publication. Articles are distributed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which allows sharing as long as the author and the original source are properly credited.