Healthcare-associated infections: Appropriate empirical antibiotic treatment

Authors

  • Marco Antonio León-Gutiérrez <p>Instituto Mexicano del Seguro Social, Hospital de Especialidades, Centro M&eacute;dico Nacional Siglo XXI,&nbsp;Unidad de Cuidados Intensivos.&nbsp;Ciudad de M&eacute;xico</p>
  • Carlos García-Peniche <p>Instituto Mexicano del Seguro Social, Hospital de Especialidades, Centro M&eacute;dico Nacional Siglo XXI,&nbsp;Residente de ultimo a&ntilde;o de la Especialidad de Medicina Cr&iacute;tica. Ciudad de M&eacute;xico</p>
  • Suria Loza-Jalil <p>Instituto Mexicano del Seguro Social, Hospital de Especialidades, Centro M&eacute;dico Nacional Siglo XXI,&nbsp;Servicio de Infectolog&iacute;a. Ciudad de M&eacute;xico</p>
  • Leonor Serrano-Cuevas <p>Instituto Mexicano del Seguro Social, Hospital de Especialidades, Centro M&eacute;dico Nacional Siglo XXI,&nbsp;Unidad de Cuidados Intensivos.&nbsp;Ciudad de M&eacute;xico</p>
  • Laura Romero-Gutiérrez <p>Instituto Mexicano del Seguro Social, Hospital de Especialidades, Centro M&eacute;dico Nacional Siglo XXI,&nbsp;Unidad de Cuidados Intensivos. Ciudad de M&eacute;xico</p>
  • Janet Tanus-Hajj <p>Instituto Mexicano del Seguro Social, Hospital de Especialidades, Centro M&eacute;dico Nacional Siglo XXI,&nbsp;Divisi&oacute;n de Servicios Centrales. Ciudad de M&eacute;xico</p>
  • Reyna Flores-Cima <p>Instituto Mexicano del Seguro Social, Hospital de Especialidades, Centro M&eacute;dico Nacional Siglo XXI,&nbsp;Laboratorio Central. Ciudad de M&eacute;xico</p>

Keywords:

Pneumonia, Ventilator-Associated, Bacterial Infections, Anti-Bacterial Agents

Abstract

Background: Health-care Associated Infections (HAI) are one of the main causes of death in critically ill patients. The aim of this paper is to establish an appropriate empirical antibiotic treatment for the main HAI in an Intensive Care Unit (ICU).

Methods: A retrospective, observational, descriptive and analytical study of the culture results from January, 2014 to December, 2015. The causative microorganisms were identified, as well as sensitivity and antibiotic resistance.

Results: Of the three main HAI in the ICU were Ventilator Associated Pneumonia (VAP), whose most common germs were methicillin-resistant Staphylococcus aureus, Acinetobacter baumannii, Pseudomonas aeruginosa; Urinary Tract Infection Associated with Urinary Catheter (IVU-CU), Escherichia coli BLEE and Pseudomonas aeruginosa were isolated in 70%, and 56% of the bloodstream infections of the germs that caused this infection were three, the most frequent being Escherichia coli, followed by Klebsiella oxytoca and methicillin-resistant Staphylococcus aureus.

Conclusions: VAP was the most frequent HAI and resistant methicillin Staphylococcus aureus was the most prevalent in this type of infection. The proposed empiric antibiotic treatment was as follows: VAP (vancomycin plus amikacin plus meropenem), IVU-CU (meropenem) and STIs (vancomycin plus cefepime).

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Published

2018-07-17

Issue

Vol. 55 No. Suplemento 4 (2017)

Section

Original Articles

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