Clinical characteristics of patients with acute myocardial infarction treated with thrombolysis
DOI:
https://doi.org/10.24875/RMIMSS.M20000006Keywords:
ST Elevation Myocardial Infarction, Thrombolytic Therapy, Cardiac CatheterizationAbstract
Background: In patients with ST elevation myocardial infarction (STEMI) thrombolytic therapy is the optimal reperfusion strategy when primary percutaneous intervention is not available.
Objective: To determine the clinical characteristics and hospital evolution of patients with STEMI who were treated with thrombolytic therapy in the Emergency department.
Method: Retrospective and transversal study; we included all patients who were diagnosed with STEMI in the Emergency department of the Hospital General Regional No. 46 and received thrombolytic therapy, within a 12 month period.
Results: We analyzed 59 cases, with a mean age of 62.2 years old, 70% were male sex; the average age for men was 60 years (range 38-84) and for women was 71 years (range 43-87); according to the initial electrocardiogram the most common myocardial affected regions were inferior (43.8%) and extense anterior (43.8%); tenecteplase was the most used thrombolytic therapy (93%), with an average door in-needle time of 82 minutes (range 10-360 min), 52.6% met clinical criteria for reperfusion; in 49 cases a cardiac catheterism was performed in subsequent days, 49% of them was for rescue percutaneous coronary intervention; in-hospital mortality was 28%.
Conclusions: Thrombolytic therapy in STEMI is effective and increases the opportunity for preserving myocardial tissue; in our institute, its mandatory that such therapy is easily available and used, taking into account the patient referral times to a hospital with catheterism laboratory.
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