Factors associated with residual symptom burden in patients with peritoneal dialysis: a cohort study
Keywords:
Protective Factors, Symptom Assessment, Peritoneal DialysisAbstract
Background: Patients on peritoneal dialysis have residual symptoms that reduce their quality of life.
Objective: To determine the associated factors of residual symptom burden in patients with continuous ambulatory peritoneal dialysis (CAPD).
Material and methods: An observational, longitudinal, prospective and analytical study was carried out in patients with chronic kidney disease, who were candidates for peritoneal dialysis. The Palliative Care Outcome Scale-Symptoms Renal (POS-S Renal) questionnaire was applied in predialysis and 3 months after CAPD. The residual symptom burden was determined three months after CAPD with a value ≥ 8 points of the POS-S Renal questionnaire. The clinical and biochemical variables coded in a dichotomous manner were compared with the residual symptom burden. Relative risk (RR) with 95% confidence intervals and logistic regression models were calculated.
Results: Seventy patients were included. The mean of glomerular filtration rate (GFR) was 4.7 ± 2 ml/min/1.73 m2. The median of the POS-S Renal score in predialysis was 30 points, and 3 months after CAPD was 8 points. The slight symptom burden predialysis presented a RR of 0.18.
Conclusions: The slight symptom burden predialysis is a protective factor independent for residual symptom burden three months after CAPD.
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