Dyslipidemia in high cardiovascular risk patients. Initial results from the REMEXDIS-IMSS study

Authors

  • Maricruz Guadalupe Machuca-Loeza <p>Instituto Mexicano del Seguro Social, Centro M&eacute;dico Nacional del Baj&iacute;o, Hospital de Especialidades No. 1, Servicio de Cardiolog&iacute;a. Le&oacute;n, Guanajuato, M&eacute;xico.</p> http://orcid.org/0009-0009-4731-2726
  • Juan Pablo Fernández-Hernández <p>Instituto Mexicano del Seguro Social, Centro M&eacute;dico Nacional del Baj&iacute;o, Hospital de Especialidades No. 1, Servicio de Terapia Intensiva. Le&oacute;n, Guanajuato, M&eacute;xico.</p> http://orcid.org/0000-0002-6603-599X
  • Maraí Xóchitl Gutiérrez-Galván <p>Instituto Mexicano del Seguro Social, Centro M&eacute;dico Nacional del Baj&iacute;o, Hospital de Especialidades No. 1, Unidad de Cuidados Intensivos Coronarios. Le&oacute;n, Guanajuato, M&eacute;xico.</p> http://orcid.org/0000-0002-9472-7563
  • Gabriela Borrayo-Sánchez <p>Instituto Mexicano del Seguro Social, Direcci&oacute;n de Prestaciones M&eacute;dicas, Coordinaci&oacute;n de Innovaci&oacute;n en Salud. Ciudad de&nbsp;M&eacute;xico, M&eacute;xico.</p> http://orcid.org/0000-0001-8531-9923
  • Iván Cruz-Aceves <p>Centro de Investigaci&oacute;n en Matem&aacute;ticas AC, Departamento de Ciencias de la Computaci&oacute;n. Le&oacute;n, Guanajuato, M&eacute;xico.</p> http://orcid.org/0000-0002-5197-2059
  • Sergio Eduardo Solorio-Meza <p>Universidad de Guanajuato, Campus Le&oacute;n, Divisi&oacute;n de Ciencias e Ingenier&iacute;as. Le&oacute;n, Guanajuato, M&eacute;xico.</p> http://orcid.org/0000-0002-7501-6088
  • Martha Alicia Hernández-González <p>Instituto Mexicano del Seguro Social, Centro M&eacute;dico Nacional del Baj&iacute;o, Hospital de Especialidades No. 1, Divisi&oacute;n de Investigaci&oacute;n&nbsp;en Salud. Le&oacute;n, Guanajuato, M&eacute;xico.</p> http://orcid.org/0000-0002-6903-2233

DOI:

https://doi.org/10.5281/zenodo.10998739

Keywords:

Cholesterol, Hypolipidemic Agents, Myocardial Infarction, LDL

Abstract

Background: There is no national registry on dyslipidemia and low-density lipoprotein cholesterol (LDL-c) goals by risk groups for atherosclerotic cardiovascular disease (ACVD) focused on beneficiaries of the Mexican Institute for Social Security (IMSS).

Objective: To determine the frequency of dyslipidemia, LDL-c goals and patients in treatment from high and very high-risk groups of ACVD.

Material and methods: Multicenter, cross-sectional, descriptive study. This article derives from the Mexican Registry of Dyslipidemias in patients at high-risk and very high-risk of atherosclerotic cardiovascular disease (REMEXDIS-IMSS Project). Patients with high-risk and very high-risk criteria for ACVD were included.

Results: From July 2022 to March 2023, 6000 patients were included (3289 patients in the high-risk group and 2771 in the very high-risk group). The frequency of dyslipidemia was observed in 49% of the cohort. The very high-risk group presented a higher percentage of dyslipidemia in 66.8%, acute myocardial infarction in 81.0% and angina pectoris in 21.9%. The use of statins was higher in this group (93.3%) and the LDL-c goal was achieved in 72.9% (p < 0.0001).

Conclusions: The frequency of dyslipidemia is found in almost half of the population. The very high-risk group had a higher frequency of dyslipidemia, better use of statins for indication of secondary prevention, and a greater number of patients with LDL-c goals compared to the high-risk group.

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Author Biographies

  • Maricruz Guadalupe Machuca-Loeza, <p>Instituto Mexicano del Seguro Social, Centro M&eacute;dico Nacional del Baj&iacute;o, Hospital de Especialidades No. 1, Servicio de Cardiolog&iacute;a. Le&oacute;n, Guanajuato, M&eacute;xico.</p>

    Departamento de Cardiología

  • Juan Pablo Fernández-Hernández, <p>Instituto Mexicano del Seguro Social, Centro M&eacute;dico Nacional del Baj&iacute;o, Hospital de Especialidades No. 1, Servicio de Terapia Intensiva. Le&oacute;n, Guanajuato, M&eacute;xico.</p>

    Departamento de Terapia intensiva

  • Maraí Xóchitl Gutiérrez-Galván, <p>Instituto Mexicano del Seguro Social, Centro M&eacute;dico Nacional del Baj&iacute;o, Hospital de Especialidades No. 1, Unidad de Cuidados Intensivos Coronarios. Le&oacute;n, Guanajuato, M&eacute;xico.</p>

    Unidad de Cuidados Intensivos Coronarios

  • Gabriela Borrayo-Sánchez, <p>Instituto Mexicano del Seguro Social, Direcci&oacute;n de Prestaciones M&eacute;dicas, Coordinaci&oacute;n de Innovaci&oacute;n en Salud. Ciudad de&nbsp;M&eacute;xico, M&eacute;xico.</p>

    Titular de la Coordinación de Innovación en Salud del IMSS

  • Iván Cruz-Aceves, <p>Centro de Investigaci&oacute;n en Matem&aacute;ticas AC, Departamento de Ciencias de la Computaci&oacute;n. Le&oacute;n, Guanajuato, M&eacute;xico.</p>

    Cátedras Conacyt- Conahcyt

  • Sergio Eduardo Solorio-Meza, <p>Universidad de Guanajuato, Campus Le&oacute;n, Divisi&oacute;n de Ciencias e Ingenier&iacute;as. Le&oacute;n, Guanajuato, M&eacute;xico.</p>

    Profesor

  • Martha Alicia Hernández-González, <p>Instituto Mexicano del Seguro Social, Centro M&eacute;dico Nacional del Baj&iacute;o, Hospital de Especialidades No. 1, Divisi&oacute;n de Investigaci&oacute;n&nbsp;en Salud. Le&oacute;n, Guanajuato, M&eacute;xico.</p>

    Jefe de la División de investigación de la UMAE No. 1 Hospital de Especialidades, León,  Gto. Mexico

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Published

2024-05-03

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Original Articles