Multi-domain intervention program on cognitive function in community-dwelling older adults: Pilot study

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Rosalinda Sánchez-Arenas https://orcid.org/0000-0003-2043-9363
Israel Grijalva https://orcid.org/0000-0002-1860-7594
Leticia Manuel-Apolinar https://orcid.org/0000-0001-8175-4215
Oscar Orihuela-Rodríguez https://orcid.org/0000-0001-7148-5533
Lourdes Basurto-Acevedo https://orcid.org/0000-0002-2991-0433
Irene Mujica-Morales https://orcid.org/0000-0002-4608-2908
Mariela Bernabe-García https://orcid.org/0000-0001-9970-2077
Arcelia Bernal-Díaz https://orcid.org/0000-0003-3129-2360
Francisco Abraham Jiménez-Armenta https://orcid.org/0009-0009-3554-508X
Eduardo Tapia-Fuentes https://orcid.org/0009-0001-4539-5910
Daniela Hernández-González https://orcid.org/0009-0002-6048-3828
Viviana Aparicio-Barranco https://orcid.org/0009-0008-2954-5166
Yamileth Margarita Villarreal-López https://orcid.org/0009-0003-2569-8361
Ryosuke Shigematsu https://orcid.org/0000-0002-4852-1265

Keywords

Prevention, Cognitive Impairment, Older Adults, Cognition

Abstract

Background: Recent interventions to prevent cognitive impairment include aerobic-cognitive training and educational programs on cognitive function.


Objective: To compare the effectiveness of a multidomain intervention and a sports program (control) on objective cognitive function (OCF), subjective memory function (SMC), frontal assessment battery, cognitive reserve, depression, anxiety, and stress in older adults through a non-randomized study.


Material and methods: The intervention consisted of aerobics and cognitive exercises (exercise on a checkered mat) and educational motivational support. The intervention group received 60 minutes of training 3 days a week for 24 weeks, and the control group 60 minutes of physical training 2 days a week for 24 weeks. Independent older adults were included. The baseline and final values ​​of the outcome variables were obtained. The relative risk for SMC, as well as the median differences, the effect estimate, and ANCOVA for continuous variables were obtained.


Results: The characteristics of the intervention group (n = 11) and control group (n = 10) were similar at baseline, except for age. OCF, SMC, and neuropsychological symptoms showed a positive trend in the intervention group, whereas in the control group did not. The intervention was significant in SMC (RR: 0.5; 95%CI 0.4-0.8), and the control showed a substantial decrease in OCF compared with the intervention group [F(1) = 8.4; p = 0.009; դp = 0.30].


Conclusions: The results suggest that the 3-component program may be more effective than the control program in improving SMC and OCF.

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