Comment on the article: “Changes in the triglyceride-glucose index after one year of antiretroviral therapy”

Main Article Content

Md. Gonzalo Enrique Flores Guamán https://orcid.org/0009-0009-0827-0340

Keywords

HIV, Communicable Diseases, Metabolism, Dyslipidemias

Abstract

Abstract


Both HIV diagnosis and antiretroviral therapy (55.1%) increase the risk of developing lipid profile abnormalities. This has led the European Society of Cardiology, in its 2025 update on the management of dyslipidemias, to incorporate statin therapy in patients older than 40 years with an HIV diagnosis as primary prevention for atherosclerotic cardiovascular disease.


These updates not only recommend strict control of the lipid profile in this population group, but also pharmacological therapy for the prevention of future cardiovascular events.

Abstract 0 | PDF (Spanish) Downloads 0

References

1. Changes in the lipid profile in people with HIV after one year of antiretroviral therapy – the significance of immune parameters

Lembas A, Załęski A, Mikuła T, Kozłowska J, Wiercińska-Drapało A. Changes in the lipid profile in people with HIV after one year of antiretroviral therapy – the significance of immune parameters. IJID Regions. 2025;14:100602. doi:10.1016/j.ijregi.2025.100602.

2. The prevalence of dyslipidemia and its correlation with anti-retroviral therapy among people living with HIV in China: a systematic review and meta-analysis

Zhai W, Ouyang F, Zhan S, Huang Y, Fu G, Yang H, et al. The prevalence of dyslipidemia and its correlation with anti-retroviral therapy among people living with HIV in China: a systematic review and meta-analysis. Front Cardiovasc Med. 2025;12:1498165. doi:10.3389/fcvm.2025.1498165.

3. Focused Update 2025 of the 2019 ESC/EAS Guidelines for the Management of Dyslipidaemias

Mach F, Koskinas KC, Roeters van Lennep JE, Tokgözoğlu L, Badimon L, Baigent C, et al. 2025 Focused Update of the 2019 ESC/EAS Guidelines for the Management of Dyslipidaemias. Eur Heart J. 2025;[Epub ahead of print]. doi:10.1093/eurheartj/ehaf190.

4. Statin Therapy as Primary Prevention for Persons with HIV: Synopsis of Recommendations

(Artículo en PMC: normalmente requiere autor/es y revista)

HHS Antiretroviral Treatment Guidelines Panel. Statin Therapy as Primary Prevention for Persons with HIV: A Synopsis of Recommendations from the U.S. Department of Health and Human Services Antiretroviral Treatment Guidelines Panel. J Int Assoc Provid AIDS Care. [año];[volumen]:[páginas]. PMID: PMC12276830.