Chronic pain in patients with breast cancer
Main Article Content
Keywords
Postoperative, Pain, Chronic Pain, Breast Neoplasms
Abstract
Breast cancer is the most frequent cancer in women. Even though most women diagnosed with breast cancer survive, many of them experience pain as part of the disease process or as a side effect of diagnostic or therapeutic procedures. Given that chronic pain in patients with breast cancer is a complex experience, the objective of this article was to conduct a systematic review of the scientific literature available in the PubMed database in English language between January 2000 and September 2019 on the epidemiology, risk factors, clinical characteristics, preventive strategies and treatment of chronic pain in patients with breast cancer, since the knowledge of these aspects is transcendental to identify, treat and monitor patients in the long term, in order to avoid further impact on their quality of life, already altered.
References
1. Cronin-Fenton DP, Norgaard M, Jacobsen J, Garne JP, Ewertz M, Lash TL, et al. Comorbidity and survival of Danish breast cancer patients from 1995 to 2005. Br J Cancer. 2007;96(9):1462-8. doi:10.1038/sj.bjc.6603717
2. Mouridsen HT, Bjerre KD, Christiansen P, Jensen MB, Moller S. Improvement of prognosis in breast cancer in Denmark 1977-2006, based on the nationwide reporting to the DBCG Registry. Acta Oncol. 2008;47(4):525-36. doi:10.1080/02841↠02027009
3. Costa WA, Monteiro MN, Queiroz JF, Goncalves AK. Pain and quality of life in breast cancer. Clinics (Sao Paulo). 2017;72(12):758-63. doi:10.6061/clinics/2017(12)07
4. Bao T, Seidman A, Li Q, Seluzicki C, Blinder V, Meghani SH, et al. Living with chronic pain:perceptions of breast cancer survivors. Breast Cancer Res Treat. 2018;169(1):133-40. doi:10.1007/s10549-018-4670-9
5. Mejdahl MK, Andersen KG, Gärtner R, Kroman N, Kehlet H. Persistent pain and sensory disturbances after treatment for breast cancer:six year nationwide follow-up study. BMJ. 2013;346:f1865. doi:10.1136/bmj.f1865
6. Jung BF, Ahrendt GM, Oaklander AL, Dworkin RH. Neuropathic pain following breast cancer surgery:proposed classification and research update. Pain. 2003;104(1-2):1-13.
7. Couceiro TC, Menezes TC, Valenca MM. Post-mastectomy pain syndrome:the magnitude of the problem. Rev Bras Anestesiol. 2009;59(3):358-65.
8. Gahm J, Wickman M, Brandberg Y. Bilateral prophylactic mastectomy in women with inherited risk of breast cancer--prevalence of pain and discomfort, impact on sexuality, quality of life and feelings of regret two years after surgery. Breast. 2010;19(6):462-9. doi:10.1016/j.breast.2010.05.003
9. Brummett CM. Chronic pain following breast surgery. Tech Reg Anesth Pain Manag. 2011;15:124-32. doi.10.1053/j.trap.2011.07.001
10. Romero A, Torà-Rocamora I, BaréM, Barata T, Domingo L, Ferrer J, et al. Prevalence of persistent pain after breast cancer treatment by detection mode among participants in population-based screening programs. BMC Cancer. 2016:16(1);735-84. doi 10.1186/s12885-016-2768-1
11. Beyaz SG, Ergönenc JS, Ergönenc T, Sönmez ÖU, Erkorkmaz Ü, Altintoprak F. Postmastectomy pain:A cross-sectional study of prevalence, pain characteristics, and effects on quality of life. Chin Med J (Engl). 2016:129(1):66-71. doi:10.4103/0366-6999.172589
12. Meijuan Y, Zhiyou P, Yuwen T, Ying F, Xinzhong C. A retrospective study of postmastectomy pain syndrome:incidence, characteristics, risk factors, and influence on quality of life. ScientificWorldJournal. 2013;2013:159732. doi:10.1155/2013/159732
13. Bokhari FN, McMillan DE, McClement S, Daeninck PJ. Pilot study of a survey to identify the prevalence of and risk factors for chronic neuropathic pain following breast cancer surgery. Oncol Nurs Forum. 2012:39(2):E141-9. doi:10.1188/12.ONF.E141-E149
14. Juhl AA, Christiansen P, Damsgaard TE. Persistent pain after breast cancer treatment:a questionnaire-based study on the prevalence, associated treatment variables, and pain type. J Breast Cancer. 2016;19(4):447-54. doi:10.4048/jbc.2016.19.4.447
15. Kurita GP, Sjogren P. Pain management in cancer survivorship. Acta Oncol. 2015;54(5):629-34. doi:10.3109/0284X.2014.996662
16. Schou Bredal I, Smeby NA, Ottesen S, Warncke T, Schlichting E. Chronic pain in breast cancer survivors:comparison of psychosocial, surgical, and medical characteristics between survivors with and without pain. J Pain Symp Manag. 2014;48(5):852-62. doi:10.1016/j.jpainsymman.2013.12.239
17. Gärtner R, Jensen MB, Nielsen J, Ewertz M, Kroman N, Kehlet H. Prevalence of and factors associated with persistent pain following breast cancer surgery. JAMA. 2009;302(18):1985-92. doi:10.1001/jama.2009.1568
18. Forsythe LP, Alfano CM, George SM, McTieman A, Baumgartner KB, Bernstein L, et al. Pain in long-term breast cancer survivors:the role of body mass index, physical activity, and sedentary behavior. Breast Cancer Res Treat. 2013;137(2):617-30. doi:10.1007/s10549-012-2335-7
19. Johannsen M, Christensen S, Zachariae R, Jensen AB. Socio-demographic, treatment-related, and health behavioral predictors of persistent pain 15 months and 7-9 years after surgery:a nationwide prospective study of women treated for primary breast cancer. Breast Cancer Res Treat. 2015;152(3):645-58. doi:10.1007/s10549-015-3497-x
20. Alves Nogueira E, Bergmann A, do Amaral E Silva B, Padula Ribeiro AC, de Souza Abrahäo K, da Costa Leite Ferreira MG, et al. Post-mastectomy pain syndrome:incidence and risks. Breast. 2012;21(3):321-5. doi:10.1016/j.breast.2012.01.019
21. Wang L, Guyatt GH, Kennedy SA, Romerosa B, Kwon HY, Kaushal A, et al. Predictors of persistent pain after breast cancer surgery:a systematic review and meta-analysis of observational studies. CMAJ. 2016;188(14):E352-61. doi:10.1503/cmaj.151276
22. Schreiber KL, Kehlet H, Belfer I, Edwards RR. Predicting, preventing and managing persistent pain after breast cancer surgery:the importance of psychosocial factors. Pain Manag. 2014;4(6):445-59. doi:10.2217/pmt.14.33
23. van Helmond N, Timmerman H, van Dasselaar NT, van de Pol CC, Olesen SS, Drewes AM, et al. High body mass index is a potential risk factor for persistent postoperative pain after breast cancer treatment. Pain Physician. 2017;20(5):E661-71.
24. Fakhari S, Atashkhoei S, Pourfathi H, Farzin H, Bilehjani E. Postmastectomy pain syndrome. IJWHR. 2017;5(1):18-23. doi 10.15296/ijwhr.2017.04
25. Andersen KG, Duriaud HM, Jensen, HE, Kroman N, Kehlet H. Predictive factors for the development of persistent pain after breast cancer surgery. Pain. 2015;156(12):2413-22. doi:10.1097/j.pain.0000000000000298
26. VanDenKerkhof EG, Hopman WM, Goldstein DH, Wilson RA, Towheed TE, Lam M, et al. Impact of perioperative pain intensity, pain qualities, and opioid use on chronic pain after surgery:a prospective cohort study. Reg Anesth Pain Med 2012;37(1):19-27. doi:10.1097/AAP.0b013e318237516e
27. De Oliveira GS Jr, Chang R, Khan SA, Hansen NM, Khan JH, McCarthy RJ, et al. Factors associated with the development of chronic pain after surgery for breast cancer:a prospective cohort from a tertiary center in the United States. Breast J. 2014;20(1):9-14. doi:10.1111/tbj.12207
28. Kambur O, Kaunisto MA, Tikkanen E, Leal SM, Rippatti S, Kelso EA. Effect of catechol-o-methyltransferase-gene (COMT) variants on experimental and acute postoperative pain in 1000 women undergoing surgery for breast cancer. Anesthesiology. 2013;119(6):1422-33. doi:10.1097/ALN.0000000000000013
29. De Gregori M, Diatchenko L, Belfer I, Allegri M. OPRM1 receptor as new biomarker to help the prediction of post mastectomy pain and recurrence in breast cancer. Minerva Anestesiol. 2015;81(8):894-900.
30. Nissenbaum J. From mouse to humans:discovery of the CACNG2 pain susceptibility gene. Clin Genet. 2012:82(4):311-20. doi:10.1111/j.1399-0004.2012.01924.x
31. Habib AS, Kertai MD, Cooter M, Greenup RA, Hwang S. Risk factors for severe acute pain and persistent pain after surgery for breast cancer:a prospective observational study. Reg Anesth Pain Med. 2019;44(2):192-9. doi:10.1136/rapm-2018-000040
32. Cho AR, Kwon JY, Kim KH, Lee HJ, Kim HK, Kim ES, et al. The effects of anesthetics on chronic pain after breast cancer surgery. Anesth Analg. 2013;116(3):685-93. doi:10.1213/ANE.0b013e31827ee372
33. Langford DJ, Paul SM, West C, Levine JD, Hamolsky D, Elboim C, et al. Persistent breast pain following breast cancer surgery is associated with persistent sensory changes, pain interference, and functional impairments. J Pain. 2014;15(12):1227-37. doi:10.1016/j.jpain.2014.08.014
34. Steyaert A, Forgot P, Dubois V, Lavand`homme P, De Kock M. Does the perioperative analgesic/anesthetic regimen influence the prevalence of chronic pain after mastectomy. J Clin Anesth. 2016;33;20-5. doi:10.1016/j.jclinane.2015.07.010
35. Cheng GS, Ilfeld BM. An evidence-based review of the efficacy of perioperative analgesic techniques for breast cancer-related surgery. Pain Med. 2017;18(7):1344-56. doi:10.1093/pm/pnw172
36. Larsson IM, Sorensen JA, Bille C. The post-mastectomy pain syndrome- A systematic review of the treatment modalities. Breast J. 2017;23(3):338-43. doi:10.1111/tbj.12739
Article Sidebar
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Authors retain their copyright and grant the Revista Médica del IMSS the right of first publication. Articles are distributed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which allows sharing as long as the author and the original source are properly credited.