Immune thrombocytopenia secondary to COVID-19: a case report

Main Article Content

Carlos Adrián Pérez-Martínez http://orcid.org/0000-0002-1937-0584
Brandon Enrique Casados-Rodriguez http://orcid.org/0000-0002-1249-4111
Fernando Padilla-Santamaría http://orcid.org/0000-0001-5535-1332

Keywords

COVID-19, Thrombocytopenia, Coronavirus Infections, Pandemics

Abstract

Background: The SARS-CoV-2 virus, which emerged in late 2019 in Wuhan province, China, has shown a wide spectrum of manifestations, some of which it shares with some autoimmune disorders. Until now, the association of SARS-CoV-2 with immune thrombocytopenia (ITP) is poorly understood, since the mechanisms that explain the complex relationship between these two prothrombotic states are still unknown.


Clinical case: It is presented the case of a 66-year-old woman, with no chronic disease history, who arrived at the Emergency Department due to respiratory symptoms. It was carried out a polymerase chain reaction with reverse transcriptase, which was positive for SARS-CoV-2. Isolated thrombocytopenia was found in laboratory studies, which was protocolized by ruling out other causes and finally diagnosing ITP secondary to COVID-19. Intravenous steroids treatment was given observing a complete recovery in platelet levels.


Conclusions: Until now, the association of IPT and COVID-19 is unclear and presents challenges in treatment. Steroids continue to be the first choice with the indication to reduce their dose and duration to the minimum necessary. Other second-line treatments present more questions than answers in the context of this pandemic.

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