Atypical clinical and mortality in older adults hospitalized with COVID-19 pneumonia

Authors

  • Tlalnelli Valencia-Blancas Instituto Mexicano del Seguro Social, Hospital General Regional No. 2, Servicio de Geriatría. Ciudad de México, México https://orcid.org/0009-0006-4263-5604
  • Lucia Herlinda Pérez-Orozco Instituto Mexicano del Seguro Social, Hospital General de Zona No. 27, Servicio de Geriatría. Ciudad de México, México https://orcid.org/0000-0002-5561-7046
  • Verónica Duran-Gómez Instituto Mexicano del Seguro Social, Hospital General de Zona No. 27, Servicio de Geriatría. Ciudad de México, México https://orcid.org/0000-0003-2646-8421
  • Evelín García-Barboza Instituto Mexicano del Seguro Social, Hospital General de Zona No. 27, Servicio de Medicina Interna. Ciudad de México, México https://orcid.org/0000-0002-4110-1356
  • Roberto Rivelino López-Anguiano Instituto Mexicano del Seguro Social, Órgano de Operación Administrativa Desconcentrada Ciudad de México Norte, Coordinación Auxiliar Médica de Investigación en Salud. Ciudad de México, México https://orcid.org/0000-0002-2108-8721

DOI:

https://doi.org/10.5281/zenodo.15178449

Keywords:

Signs and Symptoms, COVID-19, Pneumonia, Elderly, Mortality

Abstract

Background: Pneumonia caused by SARS-CoV-2 is a public health problem. Older adults are vulnerable and the atypical presentation delays diagnosis and increases mortality. In this group the atypical clinical manifestations are more frequent.

Objective: To identify the clinical manifestations and mortality of COVID-19 pneumonia in hospitalized older adults.

Material and methods:  A comparative cross-sectional observational study was carried out, from July 1, 2020, to December 31, 2021, in a general hospital of Mexico City. Patients aged 60 years or more who were hospitalized with a diagnosis of COVID-19 were included.

Results: 267 older adults participated; 53.9% were men, with a median age of 74 years. The most frequent comorbidities in this population were type 2 diabetes mellitus (T2DM), hypertension and chronic obstructive pulmonary disease (COPD). 41.2% showed atypical presentation of the disease; mortality in the studied population was 53.5%.

Conclusions: The atypical presentation of COVID-19 pneumonia is common in adults over 60 years of age and it increases significantly as they become older. The absence of typical symptoms of pneumonia and the ignorance of the most common signs could delay diagnosis and timely care in this age group, which may increase complications and mortality.

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Author Biographies

  • Tlalnelli Valencia-Blancas, Instituto Mexicano del Seguro Social, Hospital General Regional No. 2, Servicio de Geriatría. Ciudad de México, México

    Servicio de Geriatría, Médico No familiar, Geriatra 

  • Lucia Herlinda Pérez-Orozco, Instituto Mexicano del Seguro Social, Hospital General de Zona No. 27, Servicio de Geriatría. Ciudad de México, México

    Servicio de Geriatría, Médico No familiar, Geriatra 

  • Verónica Duran-Gómez, Instituto Mexicano del Seguro Social, Hospital General de Zona No. 27, Servicio de Geriatría. Ciudad de México, México

    Servicio de Geriatría, Médico No familiar, Geriatra 

  • Evelín García-Barboza, Instituto Mexicano del Seguro Social, Hospital General de Zona No. 27, Servicio de Medicina Interna. Ciudad de México, México

    Servicio de Medicina Interna, Médico No Familiar, Medicina Interna

  • Roberto Rivelino López-Anguiano, Instituto Mexicano del Seguro Social, Órgano de Operación Administrativa Desconcentrada Ciudad de México Norte, Coordinación Auxiliar Médica de Investigación en Salud. Ciudad de México, México

    Coordinación de Planeación y Enlace Institucional

    Coordinador Auxiliar Médico de Investigación en Salud

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Published

2025-06-19

Issue

Section

Original Articles