Artificial intelligence algorithm for bone age estimation

Main Article Content

Dra. Catalina Peralta Cortázar https://orcid.org/0000-0002-8905-9863
Dra. Zulem Santiago Loya https://orcid.org/0009-0009-0811-556X
Dra. Talia Minerva Rivera Villanueva https://orcid.org/0000-0003-0186-9720
Dr. Daniel Omar Pérez Godínez https://orcid.org/0009-0006-0237-3347
Dr. Oscar Abraham José Padilla Solís https://orcid.org/0009-0000-0043-5512
Dr. Agustín Ramiro Urzúa González https://orcid.org/0000-0002-9403-0686
Dra. Alma Patricia González https://orcid.org/0000-0002-3401-7519
Carlos Paque-Bautista https://orcid.org/0000-0002-2658-0491
Dr. José Luis Felipe Luna Anguiano https://orcid.org/0000-0003-3739-8334
Gloria Patricia Sosa-Bustamante https://orcid.org/0000-0002-8460-4965

Keywords

Artificial Intelligence, Age Determination by Skeleton, Radiography, Child, Adolescents

Abstract

Abstract  


Background: Bone age (BA) estimation with automated methods can eliminate interindividual variation.


Objective: To evaluate BA by creating an artificial intelligence (AI) algorithm in a pediatric population from the Bajío region of Mexico.


Material and methods: Observational, cross-sectional, retrospective, analytical study. Left-hand radiographs of children under 18 years of age, obtained from the Radiology Department database were included to create the AI ​​algorithm for estimating BA. The BA result obtained by AI was compared with that obtained by 2 expert observers using the Greulich and Pyle method.


Results: 271 radiographs were analyzed to assess BA and this was similar between observers 1, 2, and AI when considering all images (p = 0.68). The time taken to estimate BA was longer with AI (p < 0.001). AI measurement showed no differences between chronological age (CA) and BA when considering both the total number of images (p = 0.12) and when they were distributed by age group: < 6 years, 6 to < 10 years, and ≥ 10 years (p = 0.60, p = 0.06, p = 0.67, respectively). The highest EO concordance correlation coefficients (CCCs) were recorded when all images were evaluated (observer 1 and 2, observer 1 and AI, and observer 2 and AI [p < 0.001, in all 3 scenarios]).


Conclusions: The AI ​​algorithm allows for objective estimation of BA in children and adolescents as a first training approach; its refinement will optimize its use and utility in clinical practice.

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