Manejo de pseudoaneurismas asociados a tratamientos endovasculares en tercer nivel de atención
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Palabras clave
Aneurisma Falso, Trombina, Procedimientos Quirúrgicos Vasculares
Resumen
Introducción: los pseudoaneurismas se producen cuando se lesiona la pared de un vaso sanguíneo y la sangre que se filtra se acumula en el tejido circundante, con una prevalencia del 0.5 al 2%. Su etiología se asocia principalmente a punción arterial, tamaño de aguja e introductor, uso de ultrasonido (US), duración o complejidad del procedimiento, así como al uso de anticoagulación y de dispositivos de cierre. Entre los factores de riesgo se incluyen edad ≥ 75 años, sexo mujer, enfermedad renal crónica, hipertensión arterial sistémica, diabetes mellitus tipo 2, arritmia cardíaca, presencia de tejidos infectados y múltiples intentos de punción.
Objetivo: analizar protocolos de manejo de pseudoaneurismas secundarios a procedimientos endovasculares en una unidad de tercer nivel de atención del occidente de México.
Material y métodos: estudio transversal analítico con componente longitudinal. Se evaluaron expedientes electrónicos y reportes de US con diagnóstico de pseudoaneurisma en pacientes sometidos a procedimientos endovasculares, del 1 de enero al 31 de diciembre de 2022. Se consideró estadísticamente significativo un valor p ≤ 0.05.
Resultados: se evaluaron 48 pacientes: Grupo 1 (tratamiento conservador, n = 27) y Grupo 2 (invasivo, n = 21). Grupo 2 frente a Grupo 1: edad promedio (62.67 ± 16.93 frente a 66.48 ± 11; p = 0.018). Tipo de procedimiento: cateterismo cardíaco, angioplastia periférica e implantación de válvula aórtica percutánea; tiempo (días) solicitud de valoración (158 ± 34.4 frente a 6.86 ± 1.32; p = 0.032); acceso femoral (62% frente a 52%; p = 0.125); tamaño del saco ≥ 3 cm (81% frente a 22%; p = 0.001).
Conclusiones: 56% se resolvió con manejo conservador y 44% requirió tratamiento invasivo.
Referencias
1. Rao SV, O’Donoghue ML, Ruel M, et al. 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2025. doi: 10.1161/CIR.0000000000001309.
2. Barker CM, Dahm C. Femoral Access, Hemostasis, and Complications for Transcatheter Aortic Valve Replacement. Interv Cardiol Clin. 2021;10:423-430. doi: 10.1016/j.iccl.2021.07.001.
3. Rivera PA, Dattilo JB. Pseudoaneurysm. 2024. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 31194401.
4. Watanabe S, Kanazawa R, Uchida T, et al. Endovascular Embolization of Femoral Pseudoaneurysm Associated with Therapeutic and Diagnostic Neuroendovascular Procedures. J Neuroendovasc Ther. 2023;17:8-14. doi: 10.5797/jnet. oa.2022-0048.
5. Tulla K, Kowalski A, Qaja E. Femoral Artery Pseudoaneurysm. 2022. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2025.
6. Pino R, Casati R, Lo Giudice F, et al. Iatrogenic arterial pseudoaneurysms: treatment or prevention? Minerva Cardioangiol. 2020;68:268-270. doi: 10.23736/S0026-4725.20.05264-0.
7. Sokhal BS, Ma Y, Rajagopalan S. Femoral artery aneurysms. Br J Hosp Med (Lond). 2022;83(12):1-10. doi: 10.12968/hmed.2022.0258.
8. Bansal A, Gorsi U, Farook S, et al. Interventional radiology management of extremity pseudoaneurysms: a pictorial essay. Emerg Radiol. 2021;28:1029-1039. doi: 10.1007/s10140-021-01939-w.
9. Abou Diwan R, Kaadi L, Hachem S, et al. Pseudoaneurysms: Different ultrasound patterns, aetiologies and locations. Australas J Ultrasound Med. 2023;26:258-266. doi: 10.1002/ajum.12348.
10. Hayakawa N, Kodera S, Miyauchi A, et al. Effective treatment of iatrogenic femoral pseudoaneurysms by combined endovascular balloon inflation and percutaneous thrombin injection. Cardiovasc Interv Ther. 2022;37:158-166. doi: 10.1007/s12928-021-00764-9.
11. Wu H, Zhang L, Zhang C, et al. Non-Surgical treatment Versus Surgery for Iatrogenic Femoral Artery Pseudoaneurysms: Systematic Review and Meta-Analysis. Front Surg. 2022;9:905701. doi: 10.3389/fsurg.2022.905701.
12. Yadav R, Sharma A, Pathak S. Successful Surgical Management of Post-traumatic Superficial Femoral Artery Pseudoaneurysm with Delayed Presentation. Cureus. 2023;15:e45739. doi: 10.7759/cureus.45739.
13. Patel RK, Alagappan A, Tripathy T, et al. Lower extremity pseudoaneurysms and their interventional radiological management: a pictorial review. Emerg Radiol. 2023;30:555- 561. doi: 10.1007/s10140-023-02151-8.
14. Kim KW, Lee C, Im G, et al. Optimal thrombin injection method for the treatment of femoral artery pseudoaneurysm. J Thromb Haemost. 2024;22(5):1389-1398. doi: 10.1016/j.jtha.2023.12.040.
15. Koza Y, Kaya U. Retrospective Analysis of 120 Cases of Iatrogenic and Traumatic Peripheral Arterial Pseudoaneurysms. Eurasian J Med. 2020;52:180-184. doi: 10.5152/eurasianjmed.2019.18422.
16. Kurzawski J, Janion-Sadowska A, Zandecki L, et al. Comparison of the Efficacy and Safety of Two Dosing Protocols for Ultrasound Guided Thrombin Injection in Patients with Iatrogenic Femoral Pseudoaneurysms. Eur J Vasc Endovasc Surg. 2020;59:1019-1025. doi: 10.1016/j. ejvs.2020.01.009.
17. Huang X, Cai H, Lu SY. Iatrogenic femoral artery pseudoaneurysm surgically repaired with combined bovine pericardial roll and autologous great saphenous vein grafts. Chin J Traumatol. 2021;24(2):75-78. doi: 10.1016/j. cjtee.2020.11.001.
18. Yamazaki D, Fujihashi T, Amamizu H, et al. VIABAHN® Stent Graft Implantation for Iatrogenic Arteriovenous Fistula and Pseudoaneurysm of the Deep Femoral Artery. Case Rep Cardiol. 2024;2024:3426669. doi: 10.1155/2024/3426669.
19. Zhang HY, Chai DZ. Iatrogenic Femoral Arteriovenous Fistula and Pseudoaneurysm. Eur J Vasc Endovasc Surg. 2024;68(2):179. doi: 10.1016/j.ejvs.2024.03.020.
20. Wang Y, Zheng H, Yao W, et al. Management of traumatic peripheral artery pseudoaneurysm: A 10-year experience at a single center. J Interv Med. 2022;6:29-34. doi: 10.1016/j. jimed.2022.10.002.
21. Yang EY, Tabbara MM, Sanchez PG, et al. Comparison of Ultrasound-Guided Thrombin Injection of Iatrogenic Pseudoaneurysms Based on Neck Dimension. Ann Vasc Surg. 2018;47:121-127. doi: 10.1016/j.avsg.2017.07.029.
22. Watanabe S, Kanazawa R, Uchida T, et al. Endovascular Embolization of Femoral Pseudoaneurysm Associated with Therapeutic and Diagnostic Neuroendovascular Procedures. J Neuroendovasc Ther. 2023;17:8-14. doi: 10.5797/jnet. oa.2022-0048
23. Gorecka J, Chen JF, Shah S, et al. A hybrid approach for vascular control and repair of an expanding iatrogenic femoral artery pseudoaneurysm. J Vasc Surg Cases Innov Tech. 2020;6:460-463. doi: 10.1016/j.jvscit.2020.07.010.
24. Gummerer M, Kummann M, Gratl A, et al. Ultrasound-Guided Fibrin Glue Injection for Treatment of Iatrogenic Femoral Pseudoaneurysms. Vasc Endovascular Surg. 2020;54:497- 503. doi: 10.1177/1538574420934631.
25. Saydam O, Serefli D, Engin AY, et al. Ultrasound-guided thrombin injection for treatment of iatrogenic femoral artery pseudoaneurysms compared with open surgery: first experiences from a single institution. Ann Surg Treat Res. 2020;98:270-276. doi: 10.4174/astr.2020.98.5.270
26. Kurzawski J, Piątek Ł, Zandecki Ł, et al. Ultrasound-guided thrombin injection as a preferable method of treatment for iatrogenic pseudoaneurysms after invasive cardiovascular procedures - a single-center experience. Postepy Kardiol Interwencyjnej. 2021;17:376-380. doi: 10.5114/aic.2021.111039.xx
27. Cho HJ, Jeon CH, Kim MH, et al. Ultrasonography-guided endovascular management of femoral artery pseudoaneurysm after unintended dialysis catheterization with suture-mediated vascular closure devices. J Vasc Access. 2024;25:2031- 2035. doi: 10.1177/11297298221130895.
28. Maeno R, Taniguchi R, Suhara M, et al. Area reduction of perforation with a small-size sheath technique for iatrogenic femoral artery pseudoaneurysm with a large perforation. J Vasc Surg Cases Innov Tech. 2023;9:101235. doi: 10.1016/j. jvscit.2023.101235.
29. Oka S, Fumimoto M, Noguchi S, et al. Managing Femoral Artery Pseudoaneurysm Using Snare-Guided Through-and-Through Access With Perclose ProGlide. Cureus. 2025;17:e77650. doi: 10.7759/cureus.77650.
30. Wischmann P, Stern M, Baasen S, et al. Importance of pseudoaneurysms after TAVI - a retrospective analysis of 2063 patients. Vasa. 2025;54:50-58. doi: 10.1024/0301-1526/a001135
31. Grundmann D, Rudolph T, Adam M, et al. Procedural and Clinical Outcomes According to Ultrasound-Guided Access in TAVI: A Propensity-Matched Comparative Subanalysis From the PULSE Registry. Circ Cardiovasc Interv. 2025;18:e014771. doi: 10.1161/CIRCINTERVENTIONS.124.014771.
32. Mayer K, Gewalt S, Morath T, et al. Comparison of Vascular Closure Devices vs Manual Compression After Femoral Artery Puncture in Patients on Oral Anticoagulation - Post Hoc Analysis of the ISAR-CLOSURE Trial. J Invasive Cardiol. 2021;33(9):E709-E715. doi: 10.25270/jic/21.00081.
33. Nørgaard MW, Færch J, Joshi FR, et al. Is It Safe to Mobilize Patients Very Early After Transfemoral Coronary Procedures? (SAMOVAR): A Randomized Clinical Trial. J Cardiovasc Nurs. 2022;37(5):E114-E121. doi: 10.1097/JCN.0000000000000845.
34. Strauss SA, Ma GW, Seo C, et al. Ultrasound-guided versus anatomic landmark-guided percutaneous femoral artery access. Cochrane Database Syst Rev. 2025;3(3):CD014594. doi: 10.1002/14651858.CD014594.pub2
35. Fishkin T, Isath A, Virk HUH, et al. Ultrasound Guidance for Vascular Access for Coronary Angiogram: A Meta-Analysis of Randomized Controlled Trials. Am J Cardiol. 2023;206:70- 72. doi: 10.1016/j.amjcard.2023.08.014.
